Showing results for: "pathway" (31 results)
Cells constantly sense signals from their environment and convert them into internal actions through biochemical signalling pathways.
Alzheimer’s is a progressive neurological disorder with classic clinical symptoms such as dementia, cognitive decline, and behavioural changes, particularly in the ageing population.
Environmental pollution in densely populated regions remains a persistent challenge, particularly where cultural, religious, and social practices intersect with fragile ecosystems. While industrial emissions and vehicular pollution have received substantial scholarly attention, the environmental impact of everyday ritual and community practices
Environmental endocrine disruptors (EEDs) are natural and synthetic chemicals that interfere with endocrine system function by altering hormone synthesis, transport, metabolism, and receptor binding.
article discusses how plant synthetic biology is reshaping biofortification strategies, particularly through approaches such as heterologous pathway engineering and transporter-based redistribution
The current trajectory of epilepsy management has encountered a formidable "refractory wall." Despite the accelerated expansion of the neuropharmacological pharmacopeia,
What if one of the most powerful models for understanding the human brain were less than an inch long, transparent, and living in a small tank? Meet Danio rerio, the zebrafish.
Disorders of Gut–Brain Interaction (DGBIs), such as Functional Dyspepsia (FD) and Irritable Bowel Syndrome (IBS), present a formidable clinical impasse due to their profoundly heterogeneous and multifactorial nature.
Small fruit fly is an excellent model organism used by scientists to study various aspect of human health and diseases such as development, regeneration, wound healing, cancer and stem cell research
This architecture is essential for shielding neurons from toxins, pathogens, and fluctuations in the bloodstream, but it also creates a devastating bottleneck for modern medicine. More than 98% of small-molecule drugs and nearly all large biological therapeutics fail to cross the BBB in meaningful amounts, leaving many promising treatments for neurodegenerative disorders, brain tumors, and inflammatory diseases stranded in the circulation.
Wound healing is a complex and dynamic biological process that occurs through four overlapping phases: hemostasis, inflammation, proliferation, and maturation. To repair tissue damage, the body works intensively, thereby significantly increasing cellular metabolic demands.
Drug repurposing is reshaping medicine. Discover how changing a drug's route of administration — not the molecule itself — can unlock new therapeutic potential.
Understanding the human brain remains one of the greatest challenges in modern science. With billions of neurons forming intricate networks and constantly changing connections, the brain’s complexity makes it extremely difficult to study directly.
The gut microbiomeover 100 trillion microorganisms, communicates with the brain via the gut–brain axis, influencing mood, cognition, immunity, and stress regulation. Dysbiosis is linked to depression, anxiety, autism spectrum disorders, and neurodegenerative diseases, emphasizing its critical role in mental and neurological health.
Haploinsufficient genes show how losing one gene copy can affect brain development, increasing risk for neurodevelopmental disorders and behaviour changes.
Explaining The Reciprocity Between Your Brain and Your Belly For the past decade, the scientific community has increased its focus on mental health disorders including anxiety, depression,
Explore how Carbon Capture, Utilization, and Storage (CCUS) works, its role in hard-to-abate industries, and how geology helps trap CO₂ to combat climate change.
Tuberculosis (TB) remains one of the world's deadliest infectious diseases, claiming over a million lives each year. TB is the deadliest infectious disease known today, claiming more lives than COVID-19. TB is caused by the bacterium Mycobacterium tuberculosis. TB spreads through the air when infected people breathe, cough, sneeze,
Inhaled antibiotics deliver drugs directly to lung infections, achieving better results with fewer side effects, which is a game-changer in fighting resistance.
Discover how antigen-presenting cells like dendritic cells and macrophages are being recruited through smart particle design for vaccines and immunotherapy.
